Endocrine Abstracts

We describe a case of 31 year young lady with Type 1 Diabetes, who started experiencing reduction in insulin requirement and hypoglycaemia episodes due to an endocrine disorder following Pregnancy. She presented with recurrent episodes of documented hypoglycaemia and amenorrhea following successful pregnancy. Her basal insulin requirements fell from 36 units to 24 units per day and she required little if any insulin as bolus (0.5 unit for every 10 gm). She did not breast feed....

Over recent years, the numbers of commercially available slimming aids have increased dramatically. Whilst the majority of these aids are harmless, their interaction with normal physiology is either not understood or not brought to the attention of the customer. We report the case of a 45-year-old woman who presented with clinical and biochemical thyrotoxicosis (fT4 31.5 pmol/l, fT3 14.3 pmol/l, TSH <0.02 mIU/l). She had elevated TPO antibodies (51 IU...

Aim: Short Synacthen test has been widely used screening test for assessment of hypothalamo-pituitary-adrenal axis (HPA). The most widely used is 30 min plasma cortisol Post synacthen. We have compared 30 min cortisol with 60 min for assessment of the HPA axis of patients with known endocrine disorders and on long term steroid, opiate use and obesity (non endocrine disorder).Method: Cortisol Response to 30 and 60 min post synacthen were measured in rando...